The explosion, which was caused by a gas leak, occurred in the western province of Kermanshah on Thursday, according to local sources.
The victims were a mother and her kid, Ardeshir Rostami, the governor of Paveh city, said.
Four of those injured are in critical conditions.
The incident comes less than three weeks after the 10-story Metropol tower collapsed in Abadan, SW Iran, that left at least 41 killed. (ILKHA)