The blast occurred close to the al-Shaddadi base, which is widely considered an "illegal" US military installation in the region.
Details about the explosion and potential casualties or damage remain unclear as of Sunday night. The incident adds to the rising tensions in the region amid ongoing conflicts.
In recent weeks, US bases in both Iraq and Syria have been targeted by the Iraqi Islamic Resistance, which has conducted over 100 attacks since the beginning of Israel's offensive on Gaza. These attacks are said to be in support of the Palestinian people, following a sharp rise in violence in the Gaza Strip.
No official response from the US or further information about the explosion has been released at this time. (ILKHA)