The cause of the blast remains unknown, and there have been no immediate reports of casualties or significant damage.
The Al-Tanf base, located in Homs province near the borders of Iraq and Jordan, has been a frequent target of attacks and threats. Earlier on Sunday, several explosions were also heard at the US base in Al-Omar oil field.
The US Central Command (CENTCOM) has yet to comment on the incident. (ILKHA)